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Stay in Santa Cruz Region's best hotels!

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Review Score

Wonderful: 9+ Very Good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest Price First Star rating and price Top reviewed

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Chairu Eco Hotel

Hotel in Santa Cruz de la Sierra

Chairu Eco Hotel features a shared lounge, terrace, a restaurant and bar in Santa Cruz de la Sierra. This 4-star hotel offers a concierge service and a tour desk. This hotel is perfect ⭐️⭐️⭐️⭐️⭐️ It was very relaxing. The room is big and clean. King size double bed is fantastic. Guys at the reception is highly friendly 👍 The photos can't show the quality of hotel and rooms, in reality it is much better much better. Natural coffee on breakfast every day ❤️ and fresh papaya / watermelon juice for a couple of days. So highly recommend 👍

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9
Wonderful
838 reviews
Price from
$50.16
per night

TRYP by Wyndham Santa Cruz

Hotel in Santa Cruz de la Sierra

Located in Santa Cruz de la Sierra, a 19-minute walk from Gabriel Rene Moreno Autonomous University, TRYP by Wyndham Santa Cruz has accommodations with an outdoor swimming pool, free private parking,... Immaculately designed and maintained. Great reception staff.

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9
Wonderful
437 reviews
Price from
$67.15
per night

YVY CASA HOTEL

Hotel in Samaipata

Located in Samaipata, 6.1 miles from Samaipata Fort, YVY CASA HOTEL provides accommodations with a garden, free private parking and a terrace. Beautiful spot. Wonderful hosts. Superb breakfast, great atmosphere, genuinely great people. They’ve done an amazing job with the building, and it seems more to come…Gaudí is magical.

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9.2
Wonderful
262 reviews
Price from
$42.75
per night

Marriott Santa Cruz de la Sierra Hotel

Hotel in Santa Cruz de la Sierra

Marriott Santa Cruz de la Sierra Hotel has an outdoor swimming pool, fitness center, a shared lounge and terrace in Santa Cruz de la Sierra. the staff was exceptionally well trained, kindly and helpful

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9.1
Wonderful
312 reviews
Price from
$110.40
per night

Cosmopolitano Hotel Boutique

Hotel in Santa Cruz de la Sierra

Offering an outdoor pool, Cosmopolitano Hotel Boutique is located in the historical center of Santa Cruz de la Sierra. Guests can enjoy the on-site bar. Nice , chic hotel. Comfortable rooms, good wifi, and breakfast. Tiny pool. Good location. The housekeeping guy was very friendly and helpful.

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9.1
Wonderful
887 reviews
Price from
$84.39
per night

La Vida es Bella

Hotel in Samaipata

Located in Samaipata, 5.6 miles from Samaipata Fort, La Vida es Bella provides accommodations with a garden, free private parking, a shared lounge and a terrace. Beautiful place! Really quiet and relaxing and the staff was so helpful and kind. Can't recommend this place enough and we look forward to come back!

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9.3
Wonderful
113 reviews
Price from
$60
per night

El Pueblito Hotel Boutique

Hotel in Samaipata

Located in Samaipata, 7 miles from Samaipata Fort, El Pueblito Hotel Boutique has accommodations with an outdoor swimming pool, free private parking, a garden and a shared lounge. We loved the charm, comfort and friendly, helpful staff.

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9.5
Exceptional
223 reviews
Price from
$87
per night

Alfonsina Hotel Boutique

Hotel in Santa Cruz de la Sierra

Conveniently located only a 10-minute walk from Ventura Shopping Center, Alfonsina Hotel Boutique. offers accommodations in Santa Cruz de la Sierra. Breakfast was great and staff is friendly and helpful.

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9.4
Wonderful
391 reviews
Price from
$94.50
per night

Suite 5 Estrellas

Hotel in Santa Cruz de la Sierra

Located 1.3 miles from Gabriel Rene Moreno Autonomous University, Suite 5 Estrellas offers 5-star accommodations in Santa Cruz de la Sierra and has a garden, a restaurant and a bar.

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9.2
Wonderful
5 reviews
Price from
$28
per night

Hostal Juanita

Hotel in Vallegrande

Hostal Juanita is offering accommodations in Vallegrande. This 1-star hotel offers a shared lounge and room service. There's a terrace and guests can use free WiFi and free private parking. Centrally located. Beautifully decorated. Comfortable bed. Hot shower. Good Wi-Fi. Flexible checkout. Delicious breakfast. And very friendly and helpful staff (two sisters).

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9
Wonderful
10 reviews
Price from
$26
per night

Hotels with extra health and safety measures

Find hotels in Santa Cruz Region with added hygiene measures plus high cleanliness ratings

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Most-booked hotels in Santa Cruz Region in the past month

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